Molecular Cloning and Functional Studies of Neurospora crassa KIF1, a New Member of the UNC-104/KIF1 Family of Kinesin-like Proteins
نویسندگان
چکیده
KIF1, a new short member of the UNC104/KIF1-Family of Kinesins.
منابع مشابه
The UNC-104/KIF1 family of kinesins.
Most UNC-104/KIF1 kinesins are monomeric motors that transport membrane-bounded organelles toward the plus ends of microtubules. Recent evidence implies that KIF1A, a synaptic vesicle motor, moves processively. This surprising behavior for a monomeric motor depends upon a lysine-rich loop in KIF1A that binds to the negatively charged carboxyl terminus of tubulin and, in the context of motor pro...
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Mitochondria utilize diverse cytoskeleton-based mechanisms to control their functions and morphology. Here, we report a role for kinesin-like protein KLP6, a newly identified member of the kinesin family, in mitochondrial morphology and dynamics. An RNA interference screen using Caenorhabditis elegans led us to identify a C. elegans KLP-6 involved in maintaining mitochondrial morphology. We clo...
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تاریخ انتشار 2004